Last year I picked overall at a 57% success rate, but just .500 for the locks. The former was my best such effort. Hopefully those among us who live in states with more progressive attitudes towards gambling can use these to make some money.
Ohio State -38.5 v. Oregon State
I'd normally bet the other way on such a big number, but Ohio State may be one of the three best teams in the country, while Oregon State is one of the three worst power 5 programs with a brand new, first time head coach (and Ohio State will play 2 such programs this year). Something like 52-6 is definitely on the table.